Rotary movement of DNA rotors on nanopores. Leading row: Uncooked movie from the Cy5 channel of each and every rotor. Middle row: corresponding one-particle localization final results of both finishes from the DNA rotors. The situation of the current body is marked as orange and blue dots, and also the trajectory of The ten frames just before The existing frame is revealed as sound lines.
Our group research bacterial cell division and it is aiming to constitute a ‘base up biology’ in artificial cells which will autonomously divide. Our principal curiosity lies in cell division, chromatin structure, and spatial Manage.
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2007, first actual-time detection of strand Trade in homologous recombination by RecA; discovery of the minimal persistence size of finishes of microtubules; and fixed the mechanism of biosensing with carbon nanotubes
That is a aspiration of mine and we established to work that has a scrumptious dose of naivety. This is certainly something that will most likely generate magnificent ends in the longer phrase, but that doesn't matter. You should not only want to work to the concerns of tomorrow, but in addition over the queries of the day immediately after tomorrow.’
Our investigation ranges through the biophysics of DNA to artificial cells and outside of. You should take a look ceesdekker.net under with the spectrum of our recent tasks.
All parameters have been a similar for every panel in this video, except for the Preliminary placement from the 6hb rod (proven in blue) about the nanopore. Simulations that terminated early as a consequence of translocation of your rod through the pore are marked by a grey track record.
Researching DNA loop extrusion by SMC proteins for chromosome architecture with solitary-molecule assays.
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Quite cool, but that wasn’t actually where by my curiosity lay. I planned to pioneer And that i had the feeling which was now not achievable, since the most interesting basic insights experienced now been uncovered. But my area had formulated many interesting new equipment to evaluate individual molecules. I decided that I wished to utilize this to biology, to have a look at it from a physical perspective.’
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Dekker heeft fundamentele ontdekkingen gedaan op het gebied van koolstof nanobuisjes. Mede vanwege deze werkzaamheden is hij al jaren de meest geciteerde fysicus in Nederland. Tegenwoordig onderzoekt hij met enkel-molecuultechnieken de biofysica van moleculen in de biologische cel. Dekker is naast zijn wetenschappelijk werk ook bekend vanwege zijn belangstelling voor de relatie tussen geloof en wetenschap en de discussie rond smart structure in 2005. (nl)